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Chicken Alfredo Casserole

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Chicken Alfredo Casserole is a creamy, cheesy, and comforting baked pasta dish featuring tender chicken, penne pasta, and a rich Alfredo sauce. Topped with melted mozzarella and cheddar cheese, this easy-to-make casserole is perfect for busy weeknights and family gatherings.

  • Total Time: 45 minutes
  • Yield: 6 servings

Ingredients

  • 3 boneless, skinless chicken breasts, cut into bite-sized pieces
  • 1 small red onion, chopped
  • 3 cloves garlic, minced
  • 16 oz (450g) penne pasta
  • 15 oz (425g) jar Alfredo sauce
  • 1½ cups shredded mozzarella cheese, divided
  • ¼ cup milk
  • 1 cup shredded cheddar cheese
  • Salt and freshly ground black pepper, to taste
  • Fresh parsley, chopped (optional, for garnish)

Instructions

  • Preheat the Oven: Preheat to 350°F (175°C). Lightly grease a 9×13-inch casserole dish.
  • Cook the Chicken: In a skillet over medium heat, cook chicken until no longer pink (5-7 minutes). Season with salt and pepper. Add onion and garlic, cooking for 2-3 more minutes. Remove from heat.
  • Cook the Pasta: Boil salted water and cook penne according to package instructions until al dente. Drain.
  • Mix the Casserole: In a bowl, combine cooked chicken, pasta, Alfredo sauce, 1 cup mozzarella, and milk. Stir to combine.
  • Assemble & Bake: Spread the mixture in the casserole dish. Sprinkle remaining mozzarella and cheddar on top.
  • Bake: Bake for 25 minutes or until the cheese is melted and bubbly.
  • Serve: Let cool slightly before serving. Garnish with fresh parsley

Notes

  • Add Veggies: Mix in broccoli, spinach, mushrooms, or bell peppers.
  • Swap the Protein: Use shrimp, turkey, or rotisserie chicken.
  • Spicy Kick: Add red pepper flakes or cayenne pepper.
  • Cheese Variations: Substitute cheddar with Parmesan, Monterey Jack, or Swiss.
  • Crunchy Topping: Sprinkle panko breadcrumbs mixed with melted butter on top before baking.
  • Author: Sophia
  • Prep Time: 20 minutes
  • Cook Time: 25 minutes
  • Category: Dinner, Casserole
  • Method: Baking
  • Cuisine: American, Italian-Inspired