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High-Protein Spinach and Artichoke Chicken Casserole

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This High-Protein Spinach and Artichoke Chicken Casserole combines tender chicken, creamy Greek yogurt, cottage cheese, and a medley of spinach and artichokes for a hearty, low-carb meal. Packed with protein and flavor, this easy casserole is perfect for family dinners or meal prep!

  • Total Time: 45 minutes
  • Yield: 6 servings

Ingredients

  • 2 lbs boneless, skinless chicken breasts, cooked and shredded
  • 1 (14 oz) can artichoke hearts, drained and chopped
  • 1 (10 oz) package frozen spinach, thawed and drained
  • 1 cup plain Greek yogurt
  • 1 cup cottage cheese
  • 1 cup shredded mozzarella cheese
  • ½ cup grated Parmesan cheese
  • 2 cloves garlic, minced
  • 1 teaspoon onion powder
  • Salt and pepper to taste

Instructions

  • Preheat Oven:
    • Preheat your oven to 375°F (190°C).
  • Prepare the Mixture:
    • In a large mixing bowl, combine shredded chicken, chopped artichoke hearts, thawed spinach, Greek yogurt, cottage cheese, minced garlic, onion powder, salt, and pepper. Mix thoroughly.
  • Assemble the Casserole:
    • Grease a 9×13-inch baking dish.
    • Spread the chicken mixture evenly in the dish, then sprinkle shredded mozzarella and grated Parmesan on top.
  • Bake:
    • Bake in the preheated oven for 25–30 minutes, or until hot, bubbly, and the cheese is golden brown.
  • Serve:
    • Let the casserole cool for a few minutes, garnish with fresh parsley if desired, and serve warm.

Notes

  • For a keto-friendly version, use full-fat yogurt and cottage cheese.
  • Add mushrooms, bell peppers, or zucchini for extra vegetables.
  • To reheat, warm leftovers in the microwave or oven for a fresh-from-the-oven taste.
  • Author: Sophia
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: American
  • Diet: Gluten Free